{"id":13993,"date":"2022-01-13T17:29:56","date_gmt":"2022-01-13T17:29:56","guid":{"rendered":"https:\/\/www.fetaldna.it\/monogenic-fetal-diseases\/"},"modified":"2024-12-16T12:46:38","modified_gmt":"2024-12-16T12:46:38","slug":"monogenic-fetal-disease","status":"publish","type":"page","link":"https:\/\/www.fetaldna.it\/en\/monogenic-fetal-disease\/","title":{"rendered":"Monogenic Fetal Disease"},"content":{"rendered":"

[vc_row full_width=”stretch_row” css=”.vc_custom_1642094601196{padding-top: 100px !important;padding-bottom: 50px !important;background-image: url(https:\/\/www.fetaldna.it\/wp-content\/uploads\/2019\/04\/header_mom.jpg?id=10022) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column css=”.vc_custom_1642094611151{padding-top: 100px !important;padding-bottom: 100px !important;}”][\/vc_column][\/vc_row][vc_row softing_row_prepad=”ptb-30″][vc_column][vc_custom_heading text=”Monogenic Fetal Diseases” font_container=”tag:h2|text_align:center|color:%23f2483e” use_theme_fonts=”yes”][vc_column_text]<\/p>\n

The Fetal Monogenic Diseases level analyzes specific diseases associated with single genes (monogenic diseases).<\/h3>\n

[\/vc_column_text][vc_column_text css=”.vc_custom_1646349178760{padding-top: 3% !important;}”]Genetic disorders can be inherited in an autosomal dominant<\/strong> (one parent is affected), autosomal recessive<\/strong> (both parents are healthy carriers), or sex chromosome-associated manner<\/strong>. Some genetic disorders also have a de novo<\/strong><\/em> onset, that is, not transmitted by parents but produced in a casual way.<\/p>\n

With the exception of beta thalassemia, the autosomal recessive genetic disorders analyzed have no symptomatic effect in the healthy carrier; for this reason there is a risk that two apparently healthy subjects may produce offspring affected by a disorder that both of them carry.<\/p>\n

In cases of genetic disorder with a de novo<\/em> onset, the parental analysis cannot detect any anomalies, as this is solely borne by the fetus and cannot be foreseen.[\/vc_column_text][\/vc_column][\/vc_row][vc_row softing_row_prepad=”ptb-30″][vc_column][vc_row_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Cystic Fibrosis (GENE CFTR)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349247337{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Congenital deafness (GENE GJB2)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349258363{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Beta thalassemia (GENE HBB)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349272425{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Rett syndrome (GENE MECP2)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349285087{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Hemochromatosis (GENE HFE)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349301208{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Achondroplasia (GENE FGFR3)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349317800{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Hypochondroplasia (GENE FGFR3)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349330211{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Thanatophoric dysplasia (GENE FGFR3)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349365824{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Apert Syndrome (GENE FGFR2)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349380108{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Crouzon Syndrome (GENE FGFR2)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349395092{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Leopard Syndrome (PTPN11 GENE)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349411609{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Phenylketonuria (PAH GENE)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349425375{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Noonan syndrome
\n(GENES PTPN11 \/ SOS1 \/ RAF1)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349438462{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”al congenital adrenal hyperplasia due to 21-hydroxylase deficiency (GENE CYP21A2)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349453809{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][vc_column_inner width=”1\/3″][vc_custom_heading text=”Autosomal recessive polycystic kidney (PKHD1)” font_container=”tag:h5|text_align:center” use_theme_fonts=”yes” css=”.vc_custom_1646349469155{border-top-width: 2px !important;border-right-width: 2px !important;border-bottom-width: 2px !important;border-left-width: 2px !important;padding-top: 5% !important;padding-right: 5% !important;padding-bottom: 5% !important;padding-left: 5% !important;background-color: #f7f7f7 !important;border-left-color: #f0f0f0 !important;border-left-style: solid !important;border-right-color: #f0f0f0 !important;border-right-style: solid !important;border-top-color: #f0f0f0 !important;border-top-style: solid !important;border-bottom-color: #f0f0f0 !important;border-bottom-style: solid !important;border-radius: 5px !important;}”][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row_content” softing_row_prepad=”ptb-30″][vc_column][vc_custom_heading text=”Table comparison” font_container=”tag:h2|text_align:center|color:%23f2483e” use_theme_fonts=”yes”][vc_single_image source=”external_link” custom_src=”https:\/\/www.fetaldna.it\/img\/08_ComparativeTable_FetalDNA_Monogenic_EN.png”][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row full_width=”stretch_row” css=”.vc_custom_1642094601196{padding-top: 100px !important;padding-bottom: 50px !important;background-image: url(https:\/\/www.fetaldna.it\/wp-content\/uploads\/2019\/04\/header_mom.jpg?id=10022) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column css=”.vc_custom_1642094611151{padding-top: 100px !important;padding-bottom: 100px !important;}”][\/vc_column][\/vc_row][vc_row softing_row_prepad=”ptb-30″][vc_column][vc_custom_heading text=”Monogenic Fetal Diseases” font_container=”tag:h2|text_align:center|color:%23f2483e” use_theme_fonts=”yes”][vc_column_text] The Fetal Monogenic Diseases level analyzes specific diseases associated with single genes (monogenic diseases). [\/vc_column_text][vc_column_text css=”.vc_custom_1646349178760{padding-top: 3% !important;}”]Genetic disorders can be inherited in an autosomal dominant (one parent is…<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"custom-page.php","meta":{"footnotes":""},"class_list":["post-13993","page","type-page","status-publish","hentry"," c-blog-1-item nt-post-class"],"yoast_head":"\nMonogenic Fetal Disease - FetalDNA<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fetaldna.it\/en\/monogenic-fetal-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Monogenic Fetal Disease - FetalDNA\" \/>\n<meta property=\"og:description\" content=\"[vc_row full_width=”stretch_row” css=”.vc_custom_1642094601196{padding-top: 100px !important;padding-bottom: 50px !important;background-image: url(https:\/\/www.fetaldna.it\/wp-content\/uploads\/2019\/04\/header_mom.jpg?id=10022) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column css=”.vc_custom_1642094611151{padding-top: 100px !important;padding-bottom: 100px !important;}”][\/vc_column][\/vc_row][vc_row softing_row_prepad=”ptb-30″][vc_column][vc_custom_heading text=”Monogenic Fetal Diseases” font_container=”tag:h2|text_align:center|color:%23f2483e” use_theme_fonts=”yes”][vc_column_text] The Fetal Monogenic Diseases level analyzes specific diseases associated with single genes (monogenic diseases). [\/vc_column_text][vc_column_text css=”.vc_custom_1646349178760{padding-top: 3% !important;}”]Genetic disorders can be inherited in an autosomal dominant (one parent is...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.fetaldna.it\/en\/monogenic-fetal-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"FetalDNA\" \/>\n<meta property=\"article:modified_time\" content=\"2024-12-16T12:46:38+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.fetaldna.it\\\/en\\\/monogenic-fetal-disease\\\/\",\"url\":\"https:\\\/\\\/www.fetaldna.it\\\/en\\\/monogenic-fetal-disease\\\/\",\"name\":\"Monogenic Fetal Disease - FetalDNA\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.fetaldna.it\\\/#website\"},\"datePublished\":\"2022-01-13T17:29:56+00:00\",\"dateModified\":\"2024-12-16T12:46:38+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.fetaldna.it\\\/en\\\/monogenic-fetal-disease\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.fetaldna.it\\\/en\\\/monogenic-fetal-disease\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.fetaldna.it\\\/en\\\/monogenic-fetal-disease\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.fetaldna.it\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Monogenic Fetal Disease\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.fetaldna.it\\\/#website\",\"url\":\"https:\\\/\\\/www.fetaldna.it\\\/\",\"name\":\"FetalDNA | Il test prenatale su DNA fetale\",\"description\":\"Il test prenatale di ultima generazione\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.fetaldna.it\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Monogenic Fetal Disease - FetalDNA","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.fetaldna.it\/en\/monogenic-fetal-disease\/","og_locale":"en_US","og_type":"article","og_title":"Monogenic Fetal Disease - FetalDNA","og_description":"[vc_row full_width=”stretch_row” css=”.vc_custom_1642094601196{padding-top: 100px !important;padding-bottom: 50px !important;background-image: url(https:\/\/www.fetaldna.it\/wp-content\/uploads\/2019\/04\/header_mom.jpg?id=10022) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column css=”.vc_custom_1642094611151{padding-top: 100px !important;padding-bottom: 100px !important;}”][\/vc_column][\/vc_row][vc_row softing_row_prepad=”ptb-30″][vc_column][vc_custom_heading text=”Monogenic Fetal Diseases” font_container=”tag:h2|text_align:center|color:%23f2483e” use_theme_fonts=”yes”][vc_column_text] The Fetal Monogenic Diseases level analyzes specific diseases associated with single genes (monogenic diseases). 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