{"id":9726,"date":"2017-04-29T14:20:16","date_gmt":"2017-04-29T14:20:16","guid":{"rendered":"http:\/\/www.fetaldna.it\/at-the-cutting-edge\/"},"modified":"2022-03-01T22:10:55","modified_gmt":"2022-03-01T22:10:55","slug":"why-choose-fetaldna-test","status":"publish","type":"page","link":"https:\/\/www.fetaldna.it\/en\/why-choose-fetaldna-test\/","title":{"rendered":"WHY TO CHOOSE FETALDNA TEST"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row full_width=&#8221;stretch_row&#8221; content_placement=&#8221;middle&#8221; softing_bg_attachment=&#8221;fixed&#8221; softing_lg_bgpos=&#8221;center&#8221; css=&#8221;.vc_custom_1642093982777{padding-top: 100px !important;padding-bottom: 100px !important;background-image: url(https:\/\/www.fetaldna.it\/wp-content\/uploads\/2022\/01\/Sfondo_Altamedica_3.png?id=13453) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}&#8221;][vc_column css=&#8221;.vc_custom_1641833338705{padding-top: 54px !important;padding-bottom: 100px !important;}&#8221;][\/vc_column][\/vc_row][vc_row softing_row_prepad=&#8221;ptb-30&#8243;][vc_column][vc_custom_heading text=&#8221;ADVANCED TECHNOLOGY FOR FETAL DNA ANALYSIS&#8221; use_theme_fonts=&#8221;yes&#8221;][vc_column_text]The technology underlying the analysis carried out by FetalDNA is recognized by the scientific community as<strong> the most advanced in the world<\/strong>, overcoming the limits of tests already on the market.[\/vc_column_text][\/vc_column][\/vc_row][vc_row softing_row_prepad=&#8221;ptb-30&#8243;][vc_column][vc_separator color=&#8221;custom&#8221; accent_color=&#8221;#f2483e&#8221;][\/vc_column][\/vc_row][vc_row softing_row_prepad=&#8221;ptb-30&#8243;][vc_column][vc_custom_heading text=&#8221;DISCOVER NIPT TECHNOLOGY&#8221; use_theme_fonts=&#8221;yes&#8221; link=&#8221;url:https%3A%2F%2Fwww.fetaldna.it%2Fnipt-metodologia-inipt%2F|target:_blank&#8221;][vc_column_text]The Altamedica team performs the prenatal test through specific laboratory procedures:<\/p>\n<p>Reception of blood samples<\/p>\n<p>Isolation of free circulating fetal DNA from the maternal component<\/p>\n<p>Multiple DNA analysis using latest generation massive sequencing, combining platforms for NGS (Next Generation Sequencing) and Digital PCR (Polymerase Chain Reaction)<\/p>\n<p>Bioinformatics Analysis\u00a0(<em>Release 2021<\/em>)<\/p>\n<p>Analytical result[\/vc_column_text][\/vc_column][\/vc_row][vc_row softing_row_prepad=&#8221;ptb-30&#8243;][vc_column][vc_separator color=&#8221;custom&#8221; accent_color=&#8221;#f2483e&#8221;][\/vc_column][\/vc_row][vc_row softing_row_prepad=&#8221;ptb-30&#8243;][vc_column][vc_custom_heading text=&#8221;AN IMPORTANT TEST FOR A SERENE PREGNANCY&#8221; use_theme_fonts=&#8221;yes&#8221;][vc_row_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_column_text]FetalDNA is a non-invasive test that <strong>poses absolutely no risk<\/strong> for the mother nor the fetus. It is currently the most comprehensive screening test for the study of chromosomal aneuploidies affecting the fetus.<\/p>\n<p>During pregnancy, some fragments of fetal DNA circulate in the maternal blood with a concentration that increases over 9 months, then decreases after delivery. An optimal level for proceeding with the execution of FetalDNA is obtained already <strong>after 10 weeks<\/strong> of gestation. At this time, from our clinical validation studies, it is possible to obtain a very high specificity and sensitivity of the examination.<\/p>\n<p>From the 10th week, therefore, it is possible to undergo <strong>a simple maternal blood sample<\/strong>, to investigate the presence of any genetic anomalies.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;3\/4&#8243;][vc_single_image image=&#8221;9541&#8243; img_size=&#8221;full&#8221;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row softing_row_prepad=&#8221;ptb-30&#8243;][vc_column][vc_separator color=&#8221;custom&#8221; accent_color=&#8221;#f2483e&#8221;][\/vc_column][\/vc_row][vc_row softing_row_prepad=&#8221;ptb-30&#8243;][vc_column][vc_custom_heading text=&#8221;QUICK, CLEAR AND RELIABLE RESULTS&#8221; use_theme_fonts=&#8221;yes&#8221;][vc_column_text]Thanks to our cutting-edge technology, we are able to guarantee response times within <strong>5 working days<\/strong> for all types of examinations (8 working days in the case of the FetalDNA Total Screen).<\/p>\n<p>In preclinical validation studies, the examination showed a reliability of 99.9% in detecting trisomy 21, trisomy 18 and trisomy 13, and of 95% in detecting monosomy X, with rates of false positives &lt; 0.1%.<\/p>\n<p>In particular, <a href=\"https:\/\/www.fetaldna.it\/en\/fetaldna-cariotipo\/\" target=\"_blank\" rel=\"noopener\">FetalDNA Karyotype<\/a> shows more than 99% of the fetal chromosomal aneuploidies found at birth, reaching a level of detection rate comparable with amniocentesis and CVS.<\/p>\n<p><a href=\"https:\/\/www.fetaldna.it\/en\/karyotype-plus-fetaldna\/\" target=\"_blank\" rel=\"noopener\">FetalDNA Karyotype Plus<\/a> is even more complete because it added to the study of the karyotype a very high number of small chromosomal rearrangements and the diagnosis of Maternal Cystic Fibrosis.<\/p>\n<p>The maximum levels of sensitivity are obtained with the<a href=\"https:\/\/www.fetaldna.it\/en\/fetaldna-total-screen\/\" target=\"_blank\" rel=\"noopener\"> FetalDNA Total Screen<\/a>, which reaches 100% for Hereditary Maternal Thrombophilia and for CMV \/ TOXO infections, 99.9% for the trisomies of chromosomes 21, 18, 13 and sex chromosomes, 99 % for monogenic diseases, maternal spinal muscular atrophy (SMA), and risk of preterm delivery.[\/vc_column_text][vc_row_inner softing_row_prepad=&#8221;ptb-30&#8243;][vc_column_inner width=&#8221;1\/2&#8243;][vc_custom_heading text=&#8221;<\/p>\n<h3><strong>NEGATIVE RESULT<\/strong><\/h3>\n<h4>Genetic anomaly not detected<\/h4>\n<p>&#8221; font_container=&#8221;tag:h3|text_align:left|color:%23f2483e&#8221; use_theme_fonts=&#8221;yes&#8221;][vc_column_text]The test did not detect any aneuploidy among examined chromosomes examined nor microdeletions. The reliability of the result is reported in the &#8220;Results&#8221; section of the report and in the &#8220;Test Accuracy&#8221; section of the technical report.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_custom_heading text=&#8221;<\/p>\n<h3><strong>POSITIVE RESULT<\/strong><\/h3>\n<h4>Genetic anomaly detected<\/h4>\n<p>&#8221; font_container=&#8221;tag:h3|text_align:left|color:%23f2483e&#8221; use_theme_fonts=&#8221;yes&#8221;][vc_column_text]The test produced a result compatible with a fetal chromosomal aneuploidy or with a microdeletion. This result indicates that the fetus has one of the pathological conditions indicated but, as established by the ministerial rules, it must then be confirmed by an invasive diagnostic test.<\/p>\n<p>The recommended follow-up is an invasive prenatal diagnosis test &#8211; <a href=\"http:\/\/www.altamedica.it\/amniocentesi-in-altamedica\/amniocentesi-quale-fare\/\" target=\"_blank\" rel=\"noopener\">amniocentesis<\/a> or <a href=\"http:\/\/www.altamedica.it\/villocentesi-quale-fare\/\" target=\"_blank\" rel=\"noopener\">CVS<\/a> &#8211; which will be carried out completely free of charge (sampling and analysis) at the Altamedica Healthcare Center.<\/p>\n<p>Thanks to a dedicated genetic consultation, the patient will receive a detailed explanation of the examination results. Only after confirmation of the result through amniocentesis or CVS, it is possible to resort to the Italian Law 194\/78 for voluntary termination of pregnancy.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row full_width=&#8221;stretch_row&#8221; content_placement=&#8221;middle&#8221; softing_bg_attachment=&#8221;fixed&#8221; softing_lg_bgpos=&#8221;center&#8221; css=&#8221;.vc_custom_1642093982777{padding-top: 100px !important;padding-bottom: 100px !important;background-image: url(https:\/\/www.fetaldna.it\/wp-content\/uploads\/2022\/01\/Sfondo_Altamedica_3.png?id=13453) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}&#8221;][vc_column css=&#8221;.vc_custom_1641833338705{padding-top: 54px !important;padding-bottom: 100px !important;}&#8221;][\/vc_column][\/vc_row][vc_row softing_row_prepad=&#8221;ptb-30&#8243;][vc_column][vc_custom_heading text=&#8221;ADVANCED TECHNOLOGY FOR FETAL DNA ANALYSIS&#8221; use_theme_fonts=&#8221;yes&#8221;][vc_column_text]The technology underlying the analysis carried out by FetalDNA is recognized by the scientific community as the most advanced in the world, overcoming the limits&#8230;<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"custom-page.php","meta":{"footnotes":""},"class_list":["post-9726","page","type-page","status-publish","hentry"," c-blog-1-item  nt-post-class"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - 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