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FetalDNA Basic Plus

The FetalDNA Base Plus investigates the 3 main fetal chromosomal aneuploidies related to chromosomes 21, 18,13 and the sex chromosomes X, Y and fetal sex.

Down syndrome

Trisomy of chromosome 21

It is one of the most common aneuploidy; it refers to the presence of an extra copy of chromosome 21.

Edwards syndrome

Trisomy of chromosome 18

Presence of an extra copy of chromosome 18.

Patau syndrome

Trisomy of chromosome 13

Presence of an extra copy of chromosome 13.

X, Y chromosomes

Sex chromosome aneuploidies

Numerical anomalies of the sex chromosomes.

Compared to the FetalDNA Base, the FetalDNA Base Plus integrates the aneuplodies of the sex chromosomes (anomalies affecting the sex chromosomes X, Y) which can cause language, movement and / or learning difficulties in children.

The most common of this class of aneuploidy is Turner Syndrome or X-linked Monosomy which affects women with only one copy of the X chromosome.

Other aneuplodias found with the FetalDNA Base Plus are the Trisomy of the X chromosome (XXX), the Klinefelter Syndrome and the Jacobs Syndrome.

Sex of the child available upon request.

No information is provided on the other chromosomal abnormalities.

In the event that the mother has a negative Rh factor (which can be documented and visible at the time of the FetalDNA request), it is possible to request a free fetal RH analysis.

Results are available within 5 working days (but time may increase in case of technical difficulties during DNA analysis or if patient needs to repeat the test).

The prenatal test carries out a sophisticated and reliable screening but not a diagnosis, regardless of the company and the technology used. Diagnostic certainty is provided only by invasive tests (Amniocentesis and CVS) as reported in all the guidelines and international scientific literature.

In the event that the DNA screening test (FetalDNA Base) reveals abnormalities, the Altamedica Healthcare Center offers free confirmation tests through prenatal diagnosis (CVS or Amniocentesis), within our Healthcare Center in Rome.

Table comparison

FetalDNA Basic Plus + 21 microdeletions

It is also possible to combine this level with the search for 21 microdeletions, which are anomalies characterized by the absence of a small chromosomal tract with consequent loss of gene information (microdeletions) or by the addition of supernumerary genomic material (microduplications):

DiGeorge syndrome
Jacobsen syndrome
Langer-Giedion syndrome
Wolf-Hirschhorn syndrome
Kleefstra syndrome (KS)
Phelan-Mcdermid syndrome
Smith-Magenis syndrome
1q21.1 deletion syndrome
WAGR syndrome
Potocki-Shaffer syndrome
Angelman syndrome
Rubinstein-Taybi syndrome
Koolen-de Vries syndrome
18q deletion syndrome
Alagille Syndrome (AGS)
1p36 deletion syndrome
Williams syndrome
Cri-du-chat syndrome
(deletion 5p)
Prader-Willi syndrome
(15q11-q13)
Hereditary neuropathy with susceptibility to pressure paralysis (HNPP)
Miller-Dieker syndrome or lissencephaly type 1 from LIS 1 abnormalities or Miller-Dieker syndrome (MDS)

Sex of the child available upon request.

No information is provided on the other chromosomal abnormalities.

In the event that the mother has a negative Rh factor (which can be documented and visible at the time of the FetalDNA request), it is possible to request a free fetal RH analysis.

Results are available within 5 working days (but time may increase in case of technical difficulties during DNA analysis or if patient needs to repeat the test).

The prenatal test carries out a sophisticated and reliable screening but not a diagnosis, regardless of the company and the technology used. Diagnostic certainty is provided only by invasive tests (Amniocentesis and CVS) as reported in all the guidelines and international scientific literature.

In the event that the DNA screening test (FetalDNA Base) reveals abnormalities, the Altamedica Healthcare Center offers free confirmation tests through prenatal diagnosis (CVS or Amniocentesis), within our Healthcare Center in Rome.

Table comparison